The human body is a unique complex of living microorganisms. They inhabit the surface of our skin and mucous membranes, as well as our lungs, bile ducts, reproductive organs, and biological fluids, among other places. One of the most crucial components is the gut microbiome. Gastroenterologists often emphasize that health and a strong immune system begin there. Recent research in microbiology supports this claim, according to the Daily Mail.

The Living Elixir

Scientists from the University of Copenhagen studied the health of 176 Japanese centenarians, all aged 100 and older, and found that they all share a specific set of microorganisms in their gastrointestinal tracts. The study revealed that certain strains of bacteria and viruses can enhance the gut microbiome and, consequently, positively impact overall health.

Researchers assert that, at present, medicine cannot “fix” genetic predispositions that lead to hereditary diseases. However, preventing age-related illnesses is entirely feasible. To achieve this, it is necessary to adjust the composition of our microbiota by “introducing” a mix of special cultures.

Joachim Johansen, the lead author of the study, admits, “We are always striving to understand what accounts for the extraordinarily long lifespan of some individuals.” Perhaps his team has found the key to understanding this phenomenon.

The Mechanism of Action

During their research, scientists discovered that the gut of elderly Japanese individuals contained bacteria that produce specific molecules. These molecules strengthen local immunity and make it more resilient to numerous pathogens responsible for serious diseases. It is known that about 70-80% of the entire immune system is concentrated in the gut. This means that a person with a healthy gastrointestinal tract is better equipped to resist infections by producing more antibodies. Thus, this could also be a reason for longevity, explains Mr. Johansen.

The team developed an algorithm to create a “map” of the bacteria and bacteriophages found in centenarians. They then compared the data with results from a control group consisting of adults aged 18 to 60. The study’s curator noted that the team was able to identify a significant biological diversity of microorganisms specifically in the long-lived subjects.

According to Mr. Johansen, gut health is inextricably linked to the diversity of microbes that inhabit it. It is expected that individuals with a normal level of this diversity will suffer less from age-related diseases. He also added that the knowledge gained could lead to a true revolution in extending the average lifespan of humanity by creating a microbiome with an optimal balance of viruses and bacteria that protect the body from pathological conditions.

What Do Viruses Have to Do with It?

It is known that the human microbiome is primarily composed of bacteria. In fact, in a healthy body, their numbers far exceed the body’s own cells! So why do scientists emphasize the importance of viruses in building a strong microbiota and, consequently, in extending life?

It turns out that when a bacteriophage encounters a bacterium, it only strengthens it during their interaction.

In the bodies of healthy centenarian Japanese individuals, viruses that stimulate bacteria were found. These viruses help produce specific molecules that stabilize the quality and quantity of the microbiota and combat inflammatory processes.

The research materials also indicate that record-holders for longevity exhibit higher levels of microbial hydrogen sulfide. This compound is responsible for the integrity of the intestinal mucosa and its resistance to pathogens. In turn, an intact mucosa indicates a proper balance of microorganisms in the gastrointestinal tract.

And although the specific strains in question are not currently disclosed, one thing is clear: health truly begins from within.