
We often blame fatigue on lack of sleep or stress. However, American researchers have uncovered a potential biological reason for excessive daytime sleepiness. It’s linked to certain molecules in the blood, which may determine whether you feel energetic throughout the day or struggle with a constant urge to nap, reports the Daily Mail.
Fatigue Has Its “Biological Roots”
Sleep experts from Brigham Women’s Hospital in Boston surveyed more than 6,000 people and collected blood samples, identifying seven metabolites—substances formed during metabolism. These metabolites influence the tendency toward daytime sleepiness.
- Some compounds, such as tyramine (found in fermented and overripe foods), were linked to poorer sleep quality and increased fatigue.
- Others, by contrast, had a protective effect. This is particularly true for omega-3 and omega-6 fatty acids, which are found in fish, nuts, and egg yolks. People with higher levels of these substances reported less excessive sleepiness.
The Dangers of Daytime Sleepiness
Excessive fatigue affects not only productivity and mood but also increases the risk of obesity, diabetes, and cardiovascular disease. It is estimated that up to one-third of the adult population in the U.S. suffers from it. Additionally, this condition may have different mechanisms in men and women, as hormones play a significant role.

Can Dietary Changes Help?
While more clinical trials are needed, initial results suggest that a healthy diet may reduce the risk of daytime sleepiness. Specifically, regularly consuming fatty fish, nuts, and other sources of omega-3 and omega-6 fatty acids could serve as a natural defender against fatigue.
A Step Toward a More Energetic Day
Scientists say we underestimate the impact of nutrition on sleep quality and alertness. By changing our eating habits, we can not only gain more energy but also protect our hearts and brains. Sometimes, the key to an energetic day lies not in a cup of coffee, but in a plate of fried fish or a handful of nuts.
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